Oral Immunity Tests of Dysentery Antigen in White Mice

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Abstract
Dysentery antigen, after repeated freezing and thawing, may be detoxified considerably with formalin, and oral assay of this antigen can be done in a period of 5 days of immunization, 7 days of waiting, then 2 or 3 days for completing live-culture tests, or about 2 weeks in all. The oral response in mice appears to be better against the Shiga and Sonne types than against the Hiss, Flexner, and Mt. Desert types. Possibly variable doses of the different types of organisms in the vaccine might have improved the results. The results agree with those previously reported by Cooper and Keller.

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