Effect of human C-peptide on glucose transport in in vitro incubated human skeletal muscle
- 1 December 1991
- journal article
- research article
- Published by Springer Nature in Diabetologia
- Vol. 34 (12) , 899-901
- https://doi.org/10.1007/bf00400197
Abstract
Muscle specimens from the quadriceps femoris muscle were obtained from eight healthy subjects by means of an open muscle biopsy and prepared for in vitro incubation. C-peptide at 0.5, 1.0 and 2.5 nmol/l increased 3-0-methylglucose transport by 38% (NS), 64% (pppp<0.05). In conclusion, C-peptide stimulates the rate of 3-0-methylglucose transport in in vitro incubated human skeletal muscle strips in a dose-response manner. These observations suggest that C-peptide may contribute to the regulation of carbohydrate metabolism in human skeletal muscle.Keywords
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