Calcifying synovial sarcoma

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Abstract
Analysis of the clinicopathological features and the available follow-up data in 32 patients with extensively calcified synovial sarcoma revealed an age incidence and anatomic distribution similar to that of ordinary synovial sarcomas without or with minimal calcification, but indicated a more favorable survival. The median age of the 32 patients of this series was 26 years; the predominant location of the tumor was the soft tissues of the lower extremities; its average size was 4.6 cm (range, 1.5–20 cm). All of the tumors showed a focal biphasic cellular pattern and exhibited roentgenographic or microscopic evidence of extensive calcification and/or osseous metaplasia. Of the 26 patients with follow-up information (average, 8.9 years) 17 were alive and well and six had died of their disease, two after 7 and 19 years. Three additional patients were living with no signs of disease 1 1/2, 2 1/2, and three years after diagnosis, respectively. The five-year survival rate of 82.6 percent of this series is considerably better than the reported five-year survival rates of synovial sarcoma which range from 25–51%.

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