Effect of Fermented Milk (Yogurt) ContainingLactobacillus AcidophilusL1 on Serum Cholesterol in Hypercholesterolemic Humans

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Abstract
Objective: Two controlled clinical studies were performed to examine effects of consumption of one daily serving of fermented milk (FM) (yogurt) on serum lipids. Methods: In the first study, subjects were randomly allocated to FM containing Lactobacillus acidophilus L1 of human origin or to FM containing L. acidophilus ATCC 43211 of swine origin. In this single-blind study, subjects consumed one 200 ml serving of FM daily for 3 weeks. The second study was a double-blind, placebo-controlled, cross-over study. Subjects completed a 4-week first treatment, had a 2-week washout, and completed a second 4-week treatment. In the second study subjects consumed FM containing L. acidophilus L1 or placebo FM over 4 weeks. Results: In the first study, FM containing L. acidophilus L1 was accompanied by a 2.4% (pL. acidophilus has the potential of reducing risk for coronary heart disease by 6 to 10%.