Polyvinyl-Pyrrolidon-Jod und Arginase: Einfluß auf Hornhaut-Regeneration und antivirale Wirkung*
- 1 January 1985
- journal article
- research article
- Published by Georg Thieme Verlag KG in Klinische Monatsblätter für Augenheilkunde
- Vol. 186 (01) , 25-28
- https://doi.org/10.1055/s-2008-1050866
Abstract
PVP[polyvinyl-pyrrolidone]-iodine was found to be virucidal for adenoviruses and herpes simplex virus in a concentration of 0.5%, i.e., a 1:20 dilution of Betaisodona. Similar concentrations did not delay the healing of corneal epithelium of the rabbit after experimental lesions, although the eyes were slightly irritated. A higher concentration (1.25%) caused considerable ocular irritation, and healing of the cornea was delayed or completely inhibited. Arginase, which inhibited the multiplication of adenoviruses and herpes simplex virus in cell culture, did not impair corneal healing in solutions of up to 5%.This publication has 3 references indexed in Scilit:
- IN VIVO STUDIES WITH ANTIVIRAL AGENTS*Annals of the New York Academy of Sciences, 1965
- AMINO ACID REQUIREMENTS OF HERPES SIMPLEX VIRUS IN HUMAN CELLSJournal of Bacteriology, 1964
- Dependence of adenovirus replication on arginine and inhibition of plaque formation by pleuropneumonia-like organismsVirology, 1963