Hematopoietic stem cells from mice with erythroblastosis

Publisher Website
Google Scholar
Abstract
The infection of newborn mice with a mouse erythroblastotic virus increases the number of hematopoietic stem cells in the spleen. Upon retransplantation of these stem cells into intermediate recipient mice certain growth parameters (doubling time, self renewal and extinction probability, etc.) which are abnormal when measured by techniques which avoid the intermediate recipient step, appear to be reverted toward normal values. The “normalization” of the stem cells is explained by the change in the environment supporting CFU growth during transplantation.

This publication has 7 references indexed in Scilit: