Mechanism of Chloramphenicol-Cephaloridine Synergism on Enterobacteriaceae
Open Access
- 1 June 1975
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 7 (6) , 845-849
- https://doi.org/10.1128/aac.7.6.845
Abstract
A synergistic in vitro bactericidal effect of combinations of chloramphenicol and beta-lactams on strains of Enterobacteriaceae is described. The synergism is seen with strains which are resistant to the beta-lactam and is due to chloramphenicol-induced inhibition of beta-lactamase production.Keywords
This publication has 15 references indexed in Scilit:
- Rapid Gentamicin Bioassay Using a Multiple-Antibiotic-Resistant Strain of Klebsiella pneumoniaeAntimicrobial Agents and Chemotherapy, 1973
- Drug susceptibility/resistance pattern of gram-negative uropathogens to seven cephalosporinsThe Lancet Healthy Longevity, 1973
- Bactericidal Effect of Combinations of Nalidixic Acid and Various Antibiotics on EnterobacteriaceaeAntimicrobial Agents and Chemotherapy, 1973
- R Factor-Mediated Resistance to Gentamicin in a Clinical Isolate of Escherichia coliThe Journal of Infectious Diseases, 1971
- Changing Ecology of Bacterial Infections as Related to Antibacterial TherapyThe Journal of Infectious Diseases, 1970
- Activity of Penicillinase in Staphylococcus aureus as Studied by the Iodometric MethodThe Journal of Infectious Diseases, 1970
- In vitro Activity of Chloramphenicol Combined with Cephalothin against DNase-Positive, Multiple-Antibiotic Resistant Strains of Staphylococcus epidermidisChemotherapy, 1970
- Characteristics of Aerobacter beta-lactamaseCanadian Journal of Microbiology, 1968
- Methods of testing combined antibiotic bactericidal action and the significance of the resultsJournal of Clinical Pathology, 1962
- Antagonism between Antibacterial DrugsNature, 1961