Effects of Prostaglandins E-1, E-2, F-1a and F-2a on Human Sperm Motility

Abstract
Effects of the addition of 100 .mu.g each of prostaglandin[PG]E1, PGE2, PGF1.alpha. and PGF2.alpha. were seen on the motility, fructose utilization and total ATPase activity of human spermatozoa. PGE2 enhanced sperm motility and fructose utilization and decreased the whole sperm ATPase activity. While PGE1 had no effect on any of the parameters studied, PGF1.alpha. and PGF2.alpha. decreased sperm motility to some extent. Fructose utilization was reduced after PGF1.alpha. addition only. No change in the activity of ATPase was observed after treatment with the PGF series.