Nuclear magnetic resonance and molecular dynamics studies on the interactions of the ras-binding domain of raf-1 with wild-type and mutant ras proteins
- 12 February 1999
- journal article
- Published by Elsevier in Journal of Molecular Biology
- Vol. 286 (1) , 219-232
- https://doi.org/10.1006/jmbi.1998.2472
Abstract
No abstract availableKeywords
Funding Information
- Ministry of Agriculture, Forestry and Fisheries (BMP 97-VI-5)
- Wellcome Trust
- RIKEN
- Biotechnology and Biological Sciences Research Council
- Ministry of Education, Culture, Sports, Science and Technology (06404080)
This publication has 54 references indexed in Scilit:
- Ras/Rap effector specificity determined by charge reversalNature Structural & Molecular Biology, 1996
- Differential Interaction of the Ras Family GTP-binding Proteins H-Ras, Rap1A, and R-Ras with the Putative Effector Molecules Raf Kinase and Ral-Guanine Nucleotide Exchange FactorPublished by Elsevier ,1996
- Conformational Transitions in p21ras and in Its Complexes with the Effector Protein Raf-RBD and the GTPase Activating Protein GAPBiochemistry, 1996
- The 2.2 Å crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with RaplA and a GTP analogueNature, 1995
- Quantitative Analysis of the Complex between p21 and the Ras-binding Domain of the Human Raf-1 Protein KinaseJournal of Biological Chemistry, 1995
- Phosphatidylinositol-3-OH kinase direct target of RasNature, 1994
- An NMR comparison of the changes produced by different guanosine 5'-triphosphate analogs in wild-type and oncogenic mutant p21rasBiochemistry, 1993
- Mapping the nucleotide-dependent conformational change of human N-ras p21 in solution by heteronuclear-edited proton-observed NMR methodsBiochemistry, 1993
- The GTPase superfamily: conserved structure and molecular mechanismNature, 1991
- Conformation change of effector-region residues in antiparallel β-sheet of human c-Ha-ras protein on GDP→GTPγS exchange: A two-dimensional NMR studyBiochemical and Biophysical Research Communications, 1989