An efficient procedure for the resolution of α-cyano-α-fluoro-p-tolylacetic acid (CFTA) via the diastereomeric N-carbobenzyloxy-cis-1-amino-2-indanol esters
- 9 February 2004
- journal article
- Published by Elsevier in Tetrahedron: Asymmetry
- Vol. 15 (3) , 555-563
- https://doi.org/10.1016/j.tetasy.2003.12.024
Abstract
No abstract availableKeywords
This publication has 17 references indexed in Scilit:
- Determination of the absolute configurations of α-amino esters from the 19F NMR chemical shifts of their CFTA amide diastereomersChemical Communications, 2001
- Chiral discrimination of 2-arylalkanoic acids by (1S,2R)-1-aminoindan-2-ol through the formation of a consistent columnar supramolecular hydrogen-bond network †Journal of the Chemical Society, Perkin Transactions 2, 1999
- Efficient synthesis of a new, highly versatile chiral derivatizing agent, α-cyano-α-fluoro-p-tolylacetic acid (CFTA)Chemical Communications, 1998
- Chemistry of novel compounds with multifunctional carbon structure. 9. Molecular design, synthetic studies, and NMR investigation of several efficient chiral derivatizing reagents which give very large 19F NMR .DELTA..delta. values in enantiomeric excess determinationThe Journal of Organic Chemistry, 1993
- The remarkably high reactivity of α-cyano-α-fluorophenylacetyl chloride (CFPA–Cl) towards hindered nucleophiles in enantiomeric excess determinationJournal of the Chemical Society, Chemical Communications, 1992
- NMR determination of enantiomeric purityChemical Reviews, 1991
- .alpha.-Cyano-.alpha.-fluorophenylacetic acid (CFPA): a new reagent for determining enantiomeric excess that gives very large fluorine-19 NMR .DELTA..delta. valuesJournal of the American Chemical Society, 1991
- High-field FT NMR application of Mosher's method. The absolute configurations of marine terpenoidsJournal of the American Chemical Society, 1991
- On the use of the O-methylmandelate ester for establishment of absolute configuration of secondary alcoholsThe Journal of Organic Chemistry, 1986
- Nuclear magnetic resonance enantiomer regents. Configurational correlations via nuclear magnetic resonance chemical shifts of diastereomeric mandelate, O-methylmandelate, and .alpha.-methoxy-.alpha.-trifluoromethylphenylacetate (MTPA) estersJournal of the American Chemical Society, 1973