ANTICOAGULANT EFFECTS OF SULPHATED POLYSACCHARIDES IN NORMAL AND ANTITHROMBIN III‐DEFICIENT PLASMAS

Abstract
1 Comparison of the effects of sulphated polysaccharides on thrombin-induced clotting of normal and antithrombin III-deficient plasmas suggests the involvement of antithrombin III (AT III) in the anticoagulant activities of cellulose, dextran and xylan sulphates. 2 AT III appears to play little or no role in the anticoagulant activity of carrageenans.