IMMUNOLOGICAL STUDIES WITH PLASMA EXPANDERS DERIVED FROM HUMAN PLASMA*

Abstract
It has been demonstrated that many heated preparations of plasma contain a new antigen not present in the unheated materials. The usefulness of agar diffusion techniques in detecting this new component was shown. Immunization of volunteers with the human plasma preparations in several instances led to the appearance of reactions. The difficulty in attributing the reactions to any one antigen, as well as in interpreting the significance of the reactions, has been discussed.

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