Abstract
THE PAST two decades have ushered in a new era in knowledge of the viruses and the diseases which they produce. An imposing array of new viral entities has been described and related to clinical disease. Tremendous gains have been made in understanding of the fundamental nature of these agents, their modes of dissemination and their relations to their hosts. Along with these advances has come a realization of the difficulties to be encountered in the development of therapeutic substances for treating viral disease. The sulfonamides and antibiotics have been of little use in the treatment of viral diseases other than those caused by the viruses of the psittacosis-lymphogranuloma venereum group. Although many reports concerning the therapeutic effectiveness of various drugs in viral disease have appeared—and some of these will be mentioned in this paper—it must be remembered that most of these reports have neither been substantiated nor found general acceptance. In the majority of viral diseases of particular
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