THE AGGLUTINATION OF HUMAN ERYTHROCYTES MODIFIED BY TREATMENT WITH NEWCASTLE DISEASE AND INFLUENZA VIRUS

Publisher Website
Google Scholar
Abstract
Sera from patients with infectious mononucleosis, which agglutinate human red cells modified with Newcastle disease virus (NDV), do not agglutinate human cells modified by PR-8 or Lee viruses or by normal allantoic fluid (NAF). Not all patients with infectious mononucleosis develop the capacity to agglutinate NDV-treated cells. Serum from an occasional patient with hepatitis or serum sickness may also agglutinate these cells. Anti-NDV rabbit sera contain several agglutinating factors for NDV-modified erythrocytes, at least one of which appears to be specific. The agglutinating factors in anti-PR8, anti-Lee, and anti-NAF rabbit sera are all removed by absorption with normal chick tissue. Serum from a patient with infectious mononucleosis differs from an anti-NDV rabbit serum in that it does not contain NDV agglutination-inhibition antibody.