Herpes simplex virus latency in a hyperresistant clone of mouse neuroblastoma (Cl300) cells
- 1 September 1985
- journal article
- Published by Springer Nature in Archiv für die gesamte Virusforschung
- Vol. 83 (3-4) , 319-325
- https://doi.org/10.1007/bf01309927
Abstract
Herpes simplex virus (HSV) hyperresistant neuroblastoma cells (clone Cl300 RII) were latently infected with HSV-1 if cultured in presence of HSV-neutralizing antibody for one or two passages after infection and then passaged further without antibody. By superinfecting HSV-1 latently infected Cl300 RII cells with HSV-2, progeny virus with HSV-1 characteristics was regularly rescued. Such retrieval of HSV-1 decreased with passage of the latently infected cells.Keywords
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