NERVE IMPULSE VELOCITY AND FIBER DIAMETER

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Abstract
It is well established that nerve conduction velocity varies approximately with fiber diameter. Since, however, internode length in medullated nerve varies also with fiber diameter, it is possible that velocity is a more immediate function of internode length than diameter itself. Internode length and diameter, however, do not vary concomitantly over the length of the fiber in the frog sciatic nerve. It was determined with the cathode ray oscillograph that conduction velocity in the fastest fibers of the bullfrog sciatic is 27% less in the distal fourth than in the proximal one. This is discussed in relation to available histological data, which are of such limited extent that a final conclusion is deferred.

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