Observations upon the toxic principle in the seeds of Dichapetalum toxicarium. Separation of a long-chain fatty acid containing fluorine

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Abstract
The main toxic principle in the seeds of Dichapetalum toxicarium behaves as a long-chain fatty acid containing fluorine. Upon injection into rats, or administration in the food, it induced large citric acid accumulations, especially in the heart. The toxicity is therefore due presumably to a conversion into fluorocitric acid. With kidney particles from the guinea pig, the fluoro fatty acid fraction induced citric acid accumulations.