Identification of Tn2401, a Transposon Encoding Multiresistance to Aminoglycosides
- 1 May 1983
- journal article
- research article
- Published by Microbiology Society in Microbiology
- Vol. 129 (5) , 1527-1536
- https://doi.org/10.1099/00221287-129-5-1527
Abstract
Summary: A transposable element, Tn2401, was found in a clinical isolate of Pseudomonas aeruginosa. Tn2401 had a size of 7190 nucleotides and encoded aminoglycoside 3′-phosphotransferase and aminoglycoside 6′-N-acetyltransferase. The sequence encoding the former enzyme was homologous with that of Tn903. Pseudomonas aeruginosa strains harbouring this transposon were resistant to kanamycin, neomycin, lividomycin, ribostamycin, paromomycin, netilmycin, tobramycin, dibekacin, gentamicin, sisomicin, and butirosin.Keywords
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