Adsorption of Insulin to Glass.

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Abstract
Crystalline zinc insulin in aqueous solution containing several micrograms per milliliter was allowed to come in contact with glass. The glass was first rinsed with distilled water and then with a solution of 5% gelatin. Using a fall in blood sugar in the hypophysecto-mized mouse and hypoglycemic convulsions in the normal mouse as criteria for the presence of insulin, the gelatin rinse was found to contain insulin in quantities significantly greater than could be expected owing to a lack of complete drainage of the original insulin solution from the glass. This result indicates insulin adsorbs to glass and can be eluted from it with a gelatin solution.

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