THE IN VITRO PRODUCTION OF OESTROGENS FROM PROGESTERONE BY MOUSE ADRENAL GLANDS
- 1 May 1964
- journal article
- research article
- Published by Bioscientifica in Journal of Endocrinology
- Vol. 29 (2) , 185-191
- https://doi.org/10.1677/joe.0.0290185
Abstract
SUMMARY: The capacity of the adrenal gland of the mouse to form steroids in vitro, using incubation techniques with [4-14C]progesterone, was investigated. Reasons are given for the identification of two oestrogens, 16-oxooestrone and 17-epioestriol and two adrenocorticosteroids, corticosterone and 20α-hydroxycorticosterone. The presence or absence of the X zone did not appear to influence the relative amounts of oestrogens and adrenocorticosteroids produced. No compounds which could be unequivocally characterized as androgens (C19 steroids) were found.Keywords
This publication has 15 references indexed in Scilit:
- ADRENAL ESTROGENS IN PATIENTS WITH METASTATIC BREAST CANCER1Journal of Clinical Investigation, 1958
- ISOLATION OF STEROIDS FROM A FEMINIZING ADRENAL CARCINOMAJournal of Biological Chemistry, 1957
- OBSERVATIONS ON IN VITRO ADRENAL STEROID SYNTHESIS IN THE ALBINO MOUSE1Endocrinology, 1956
- New solvent systems for the resolution of corticosteroids by paper chromatographyArchives of Biochemistry and Biophysics, 1955
- A chemical method for the determination of oestriol, oestrone and oestradiol in human urineBiochemical Journal, 1955
- Some errors in the colorimetric estimation of oestriol, oestrone and oestradiol by the Kober reactionBiochemical Journal, 1954
- THE SECRETION OF THE ADRENAL CORTEX IN THE SHEEPJournal of Endocrinology, 1953
- Methods of paper chromatography of steroids applicable to the study of steroids in mammalian blood and tissuesBiochemical Journal, 1952
- 16-SUBSTITUTED STEROIDS .4. 16-KETO-ALPHA-ESTRADIOL AND 16-KETOESTRONE1948
- On the occurrence of the œstrous cycle after X-ray sterilisation. Part III.— The periodicity of œstrus after sterilisation of the adultProceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character, 1927