First Isolation of Metallo-β-Lactamase-Producing Multiresistant Klebsiella pneumoniae from a Patient in Brazil
Open Access
- 1 January 2005
- journal article
- case report
- Published by American Society for Microbiology in Journal of Clinical Microbiology
- Vol. 43 (1) , 516-519
- https://doi.org/10.1128/jcm.43.1.516-519.2005
Abstract
A multiresistant Klebsiella pneumoniae isolate was taken from the blood of a 75-year-old patient with nosocomial pneumonia who developed septic shock and failed therapy with imipenem. The isolate presented an MIC of imipenem of 128 μg/ml, and the production of a metallo-β-lactamase was confirmed by phenotypic and genotypic techniques. We here report, for the first time, the detection of a metalloenzyme (IMP-1)-producing K. pneumoniae clinical strain in Latin America. The gene responsible for this phenotype was found to be bla IMP-1 , carried in a class 1 integron.Keywords
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