Selecting B cells and plasma cells to memory
Open Access
- 21 February 2005
- journal article
- editorial
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 201 (4) , 497-499
- https://doi.org/10.1084/jem.20050218
Abstract
Humoral immunity appears to be based on immunological memory provided by memory plasma cells, which secrete protective antibodies, and memory B cells, which react to antigen challenge by differentiating into plasma cells. How these differentiation pathways relate to each other, how cells are selected into these memory populations, and how these populations are maintained remains enigmatic.Keywords
This publication has 10 references indexed in Scilit:
- Generation of migratory antigen-specific plasma blasts and mobilization of resident plasma cells in a secondary immune responseBlood, 2005
- Early appearance of germinal center–derived memory B cells and plasma cells in blood after primary immunizationThe Journal of Experimental Medicine, 2005
- Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoireBlood, 2004
- Antigen-capturing Cells Can Masquerade as Memory B CellsThe Journal of Experimental Medicine, 2003
- Maintenance of Serological Memory by Polyclonal Activation of Human Memory B CellsScience, 2002
- Evolution of Autoantibody Responses via Somatic Hypermutation Outside of Germinal CentersScience, 2002
- Chemotactic Responsiveness Toward Ligands for CXCR3 and CXCR4 Is Regulated on Plasma Blasts During the Time Course of a Memory Immune ResponseThe Journal of Immunology, 2002
- On differences between immunity and immunological memoryCurrent Opinion in Immunology, 2002
- Survival of long-lived plasma cells is independent of antigen [In Process Citation]International Immunology, 1998
- Ueber das Zustandekommen der Diphtherie-Immunität und der Tetanus-Immunität bei ThierenDeutsche Medizinische Wochenschrift (1946), 1890