SOME EFFECTS OF INJECTING STERILE SOLUTIONS OF STREPTOKINASE-STREPTODORNASE INTO THE SUBARACHNOID SPACE OF NORMAL RHESUS MONKEYS 12

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Abstract
The injn. of sterile solns. of streptokinase and strepto-dornase into the subarachnoid space of normal rhesus monkeys invoked a vigorous polymorphonuclear pleocytosis and a positive Pandy reaction. The white counts dropped sharply within a few days and were practically normal within 2 wks. These effects were not accompanied by any sign of clinical illness in the monkeys nor by the laying down of gross exudate upon the brain of animals which were sacrificed.