Stimulating Factors and Cell Recruitment In Murine Bone Marrow Stem Cells and Emt6 Tumours

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Abstract
The role of a stimulating factor in cell recruitment and the kinetics of its secretion were investigated by in vivo and in vitro techniques. The association of these 2 methods made it possible to demonstrate that a non-cycling population liberates a factor which in turn stimulates quiescent bone marrow stem cells into DNA synthesis. It seems that undamaged cells are capable of secreting this factor. A stimulating factor responsible for cell recruitment was also demonstrated in an experimental murine mammary EMT6 tumor and the kinetics of its secretion reported.
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