Modification of seldomycin factor 5 at C-3'.
- 31 December 1977
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 31 (5) , 441-450
- https://doi.org/10.7164/antibiotics.31.441
Abstract
Attempted removal of the 3''-hydroxyl group of seldomycin factor 5 via displacement of a sulfonate ester led to 3''-epi-seldomycin factor 5. Removal of the hydroxyl group was effected by the Barton procedure. The antibacterial activity of 3''-epi- and 3''-deoxyseldomycin factor 5 against various aminoglycoside-resistant strains is discussed.This publication has 3 references indexed in Scilit:
- A new aminoglycoside antibiotic complex - The seldomycins. IV. The structure of seldomycin factor 5.The Journal of Antibiotics, 1977
- A new aminoglycoside antibiotic complex - The seldomycins. I. Taxonomy, fermentation and antibacterial properties.The Journal of Antibiotics, 1977
- Synthesis of 3'-deoxyseldomycin 5.The Journal of Antibiotics, 1977