Synthesis of Anomeric Ethyl Ketosides of 5-N-Acetyl-D-neuraminic Acid
- 1 January 1979
- journal article
- Published by Walter de Gruyter GmbH in Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie
- Vol. 360 (2) , 1253-1256
- https://doi.org/10.1515/bchm2.1979.360.2.1253
Abstract
The syntheses of anomeric ethyl ketosides of 5-N-acetyl-D-neuraminic acid are described. The alpha-anomer prepared by a modified Koenigs-Knorr procedure starting from acetochloroneuraminic acid is quantitatively cleaved by Vibrio cholerae neuraminidase. Proton-catalyzed reaction of 5-N-acetyl-D-neuraminic acid with ethanol yields the beta-anomer.Keywords
This publication has 2 references indexed in Scilit:
- Circular dichroism studies on α- and β-ketosides of 5-acetamido-3,5-dideoxy-D-glycero-D-galacto-nonulopyranosonic acid (N-acetylneuraminic acid) and of some of its derivativesCarbohydrate Research, 1975
- Synthese anomerer Sialinsäure‐methylketosideEuropean Journal of Inorganic Chemistry, 1966