The development of protein farnesyltransferase and other ras-directed therapeutics for malignant diseases
- 1 July 2000
- journal article
- Published by Informa Healthcare in Emerging Drugs
- Vol. 5 (2) , 161-199
- https://doi.org/10.1517/14728214.5.2.161
Abstract
No abstract availableThis publication has 98 references indexed in Scilit:
- α-Subunit of Farnesyltransferase Is Phosphorylatedin Vivo:Effect of Protein Phosphatase-1 on Enzymatic ActivityBiochemical and Biophysical Research Communications, 1996
- Stimulation of Membrane Ruffling and MAP Kinase Activation by Distinct Effectors of RASScience, 1996
- Ras-dependent growth factor regulation of MEK kinase in PC12 cellsScience, 1994
- Phosphatidylinositol-3-OH kinase direct target of RasNature, 1994
- Transformation of Mammalian Cells by Constitutively Active MAP Kinase KinaseScience, 1994
- Proteins regulating Ras and its relativesNature, 1993
- Triggering signaling cascades by receptor tyrosine kinasesTrends in Biochemical Sciences, 1992
- The small GTP-binding protein rac regulates growth factor-induced membrane rufflingCell, 1992
- The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factorsCell, 1992
- Isoprenylation is required for the processing of the lamin A precursor.The Journal of cell biology, 1990