STUDIES ON OBESITY. III. EFFECT OF ASCORBIC ACID ON THE INSULIN-GLUCOSE TOLERANCE CURVE

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Abstract
The effect of 500 mg of ascorbic acid given orally 4 times a day for a minimum of 3 weeks on the abnormal insulin-glucose tolerance curves in 21 obese subjects is presented. It was questionably significant in 8 patients with abnormal oral glucose tolerance curves, but in 13 patients with normal oral glucose tolerance curves, significant reversal occurred towards normal in the insulin-glucose tolerance curve, the average readings all falling within the normal range. The possible action of ascorbic acid on carbohydrate metabolism is discussed.