Reorganisation of peripheral actin filaments as a prelude to exocytosis
- 1 April 1987
- journal article
- review article
- Published by Portland Press Ltd. in Bioscience Reports
- Vol. 7 (4) , 281-288
- https://doi.org/10.1007/bf01121449
Abstract
Evidence is presented, from studies on the adrenal chromaffin cell, that reorganisation of the cortical actin network is necessary to allow granules to reach exocytotic sites in stimulated cells. This reorganisation may involve changes in actin filament cross-linking, assembly and interactions with secretory granule and plasma membranes. The possibility is discussed that cytoskeletal elements including the membrane-binding proteins caldesmon, p70 and p36 may be involved in granule-plasmalemmal interactions immediately prior to exocytosis.Keywords
This publication has 27 references indexed in Scilit:
- Nicotine‐evoked disassembly of cortical actin filaments in adrenal chromaffin cellsFEBS Letters, 1986
- Quantitative analysis of the cytosolic free calcium dependency of exocytosis from three subcellular compartments in intact human neutrophils.The Journal of cell biology, 1986
- Secretory cell actin-binding proteins: identification of a gelsolin-like protein in chromaffin cells.The Journal of cell biology, 1986
- The Membrane-Associated ‘Cortex’ of Animal Cells: its Structure and Mechanical PropertiesJournal of Cell Science, 1986
- Identification of a secretory granule-binding protein as caldesmonNature, 1986
- Purification and characterization of caldesmon77: a calmodulin-binding protein that interacts with actin filaments from bovine adrenal medulla.Proceedings of the National Academy of Sciences, 1985
- Reorganization of α-fodrin induced by stimulation in secretory cellsNature, 1985
- The structure of cortical cytoplasmPhilosophical Transactions of the Royal Society of London. B, Biological Sciences, 1982
- Dissection of stages in exocytosis in the adrenal chromaffin cell with use of trifluoperazineProceedings of the Royal Society of London. B. Biological Sciences, 1982
- Pancreatic Beta-Cell Web: Its Possible Role in Insulin SecretionScience, 1972