Approaches to the Solid Phase of a Cyclotriveratrylene Scaffold-Based Tripodal Library as Potential Artificial Receptors
- 26 August 2003
- journal article
- Published by American Chemical Society (ACS) in Journal of Combinatorial Chemistry
- Vol. 5 (6) , 794-801
- https://doi.org/10.1021/cc034003u
Abstract
Two versatile tripodal cyclotriveratrylene (CTV)-based scaffolds (7 and 9) have been prepared for the solid phase construction of libraries of tripodal artificial synthetic receptors. A 2197-member library of CTV-based tripodal receptor molecules, 20{1−13,1−13,1−13}, was prepared on the solid phase using split−mix synthesis. The CTV-based receptors contain three peptide arms; one of them is attached to the solid phase and is different from the other two identical peptide arms.Keywords
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