Regulation of rat renal (Na++K+)-adenosine triphosphatase mRNA levels by corticosterone
- 1 August 1992
- journal article
- Published by Springer Nature in Cellular and Molecular Life Sciences
- Vol. 48 (8) , 768-773
- https://doi.org/10.1007/bf02124300
Abstract
We investigated the mechanisms for glucocorticoid regulation of rat renal NaK-ATPase activity. Our findings suggest that the magnitudes of corticosterone-induced increases inα 1 mRNA andβ 1 mRNA levels are similar in the kidney of the adult adrenalectomized rats. The results also suggest that corticosterone restores NaK-ATPase activity in adrenalectomized rats prior to any enhanced sodium delivery.Keywords
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