High-Frequency Oscillatory Ventilation Compared with Conventional Mechanical Ventilation in the Treatment of Respiratory Failure in Preterm Infants

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Abstract
We conducted a multicenter randomized clinical trial to compare the efficacy and safety of high-frequency ventilation with that of conventional mechanical ventilation in the treatment of respiratory failure in preterm infants. Of 673 preterm infants weighing between 750 and 2000 g, 346 were assigned to receive conventional mechanical ventilation and 327 to receive high-frequency oscillatory ventilation.