Role of Estrogen in Sex Difference of the Electrocardiogram of the Chicken.

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Abstract
Ecg were obtained on 25 adult normal males and 31 females. Another group of males received a 15 mg pellet of diethylstilbestrol, a second pellet two weeks later, and a third after an additional two weeks. Ecg were obtained before, during and 57 days after the last administration of estrogen, or after recovery from the hormone, based upon comb size. Data demonstrate that the amplitudes of R, S and RS of the ecg of normal hens are approximately half those of normal males. Diethylstilbestrol caused a significant decrease (30-35%) in the amplitude of all waves of the ecgs of males. Fifty seven days following estrogen treatment the amplitudes increased but did not return to the normal level.

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