ANTIFUNGAL ACTION OF SALICYLANILIDE. II
- 1 January 1960
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Biochemistry and Physiology
- Vol. 38 (1) , 245-251
- https://doi.org/10.1139/y60-026
Abstract
The fungistatic activities of certain compounds structurally related to salicylanilide suggest the possible involvement of hydrogen bonding of the anilide hydrogen atom and chelation by the phenolic and amidic oxygen atoms with an enzyme(s)/enzyme system of the fungus. The inhibition of enzymes has been followed through the development of specific color reactions on salicylanilide assay plates. The participation of sulphydryl groups in the mechanism of action is suggested by these tests.Keywords
This publication has 8 references indexed in Scilit:
- Enzymes of Pathogenic FungiJournal of General Microbiology, 1953
- Cytochemical Mechanisms of Penicillin ActionJournal of Bacteriology, 1947
- Dissociation Constants of Slightly Soluble Pharmaceuticals * *From the College of Pharmacy and Department of Chemistry, University of Texas, Austin, Texas.Journal of the American Pharmaceutical Association (Scientific ed.), 1944
- On the Enzymes of certain Dermatophytes, or Ringworm FungiParasitology, 1929
- über Azofarbstoffe aus Acetessigsäure‐aniliden. (Darstellung der Acetessig‐anilide und die Konstitution der Hansagelb)Helvetica Chimica Acta, 1928
- STERIC RELATIONS IN THE ACYLATION OF AROMATIC AMINES AND AMINOPHENOLSJournal of the American Chemical Society, 1924
- Zur Kenntniss des m‐AmidophenolsEuropean Journal of Inorganic Chemistry, 1899
- Ueber das Verhalten des Anilins zu den Substitutionsproducten der Oxybenzoësäuren in höherer TemperaturEuropean Journal of Inorganic Chemistry, 1889