Chemotactic Responses of Tumor Cells to Products of Resorbing Bone
- 12 January 1979
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 203 (4376) , 176-179
- https://doi.org/10.1126/science.569363
Abstract
To explore possible mechanisms for the metastasis of malignant cells to bone, a model of tumor cell migration was developed, using Walker carcinosarcoma or malignant lymphoma cells. It was found that bone contains a factor that is strongly chemotactic for tumor cells. This factoor is released by a variety of agents that induce resorption of bone.This publication has 11 references indexed in Scilit:
- Resorbing bone is chemotactic for monocytesNature, 1978
- Relationship between the C5 Peptides Chemotactic for Leukocytes and Tumor CellsThe Journal of Immunology, 1976
- The Inhibition by Aspirin and Indomethacin of Osteolytic Tumour Deposits and Hypercalcaemia in Rats with Walker Tumour, and its Possible Application to Human Breast CancerBritish Journal of Cancer, 1973
- An Autopsy Study of Some Routes of Dissemination of Cancer of the BreastBritish Journal of Cancer, 1973
- Studies on the mechanisms of invasion in cancer. II. In vivo effects of a factor chemotactic for cancer cellsInternational Journal of Cancer, 1971
- Chemotactic Factor associated with Invasion of Cancer CellsNature, 1970
- ACUTE HYPERCALCEMIA DUE TO WALKER CARCINOSARCOMA 256 IN THE RATHormone and Metabolic Research, 1970
- THE ROLE OF SERUM COMPLEMENT IN CHEMOTAXIS OF LEUKOCYTES IN VITROThe Journal of Experimental Medicine, 1965
- Bone Resorption in Tissue Culture. Factors Influencing the Response to Parathyroid Hormone *Journal of Clinical Investigation, 1965
- INTERACTIONS BETWEEN RABBIT POLYMORPHONUCLEAR LEUCOCYTES AND STAPHYLOCOCCIThe Journal of Experimental Medicine, 1959