EFFECT OF OESTRADIOL MONOBENZOATE ON THE THE METABOLISM OF THE RAT ENDOMETRIUM

Publisher Website
Google Scholar
Abstract
The glucose uptake of isolated endometrium from castrated rats is increased by estradiol benzoate (50 y.%. subcut. in oil 48 hrs. before sacrifice.) The effect is seen anaerobically and aerobically. Glycogen breakdown and lactate formation were unaffected, O2 uptake was increased. 33% of the glucose utilized went to lactate when incubated aerobically, and 67% when anaerobic. The accelerated QO2 is accounted for by increased glucose utilization. The effect of estrogens on endometrial metabolism is believed to be chiefly by accelerating glucose utilization (i.e., hexokinase-catalyzed glucose phosphorylation by ATP.).

This publication has 4 references indexed in Scilit: