Severe Hypoglycemia Secondary to a Nonpancreatic Fibrosarcoma with Insulin Activity

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Abstract
THE syndrome of hypoglycemia secondary to a nonpancreatic tumor has been reported on several occasions.1 2 3 4 5 6 7 8 9 10 11 12 13 14 We recently studied a patient with frequent and protracted episodes of hypoglycemia that ceased when a large intrathoracic fibrosarcoma was removed. Our data suggest that the disturbance in carbohydrate metabolism was the result of secretion by the intrathoracic neoplasm of an agent with insulin activity.Case ReportM. V. (B.I.H. 82200), an 82-year-old Jewish widow, entered the Beth Israel Hospital on December 24, 1956, for the 4th time. She had been active and well until 2 months previously, when she began to experience episodes of . . .