Thyroid Function in Insulin-Dependent Diabetic Children

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Abstract
Serum concentrations of thyroxine (T4)3, 5, &3prime;tniodothyronine (T3),3,&3prime;,&5prime;-reverse triiodothyronine (rT3),T3-binding capacity (TBC) and TSH were measured in 10 children with diabetes mellitus (mean age: 12.8 ± 2yr). The children were without ketoacidosis and serum glucose concentrations were,10.64 ± 1.68 mmol/1 (SD). The mean concentrations of serum T4, T3, rT3, TBC and TSH were 116.35 ± 10.68 nmol/1 (SD), 2.81 ± 0.33 nmol/1, 0.27 ± 0.04 nmol/1, 1.087 ± 0.031 and 3.16 zh 0.9 μIU/ml, respectively, which were not significantly different from values of 10 normal control subjects (mean age: 11.6 ± 2yr). It seems therefore that the thyroid hormones and TSH levels between well controlled diabetic and healthy subjects of pediatric age do not differ significantly.