Fertility and X‐chromosome rearrangements: isodicentric X‐chromosome formation in the mother and Xp deletion in her daughter

Abstract
In the present paper we report the first example of fertility in a female with isodicentric X-formation and karyotype 45,X/46,X,del(X)(pter .fwdarw. p21.3)/46,X,idic(X)(qter .fwdarw. p21.3 ::p21.3 .fwdarw. qter). Her daughter was phenotypically almost normal and presented a 46,X,del(X)(pter .fwdarw. p21.3) karyotype in all examined cells.