IMMUNOSUPPRESSIVE EFFECT OF HUMAN PREGNANCY ZONE PROTEIN ON H‐2 INCOMPATIBLE MOUSE HEART ALLOGRAFT
- 1 November 1978
- journal article
- research article
- Published by Wiley in Acta Pathologica Microbiologica Scandinavica Section C Immunology
- Vol. 86C (1-6) , 199-201
- https://doi.org/10.1111/j.1699-0463.1978.tb02579.x
Abstract
Human pregnancy zone protein (PZP) given i.v., significantly (P < 0.001) prolonged the survival of heterotopic A/J heart transplants in A.CA recipients, compared to untreated control recipients, recipients treated with phosphate buffered saline and recipients treated with a control preparation from male serum. Apparently PZP protein exerts an nonspecific immunosuppressive effect in vivo.Keywords
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