Penicillin Sensitivity of Staphylococci

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Abstract
A SIGNIFICANT increase in penicillin resistance of Staphylococcus aureus has been reported from medical centers in this country and abroad.1 2 3 4 5 In several instances the number of penicillin-resistant strains of S. aureus was recorded as greater than 50 per cent. This trend has been generally attributed to hospital infection from carriers of penicillin-resistant organisms and to the emergence of drug-fast strains in unhealed lesions following penicillin therapy.Sherris and Florey have suggested that there is a close correlation between clinical manifestations of staphylococcal lesions and penicillin sensitivity of the infecting organisms.6 , 7 They found that acute, closed infections and deep-seated infections, acute . . .