SKIN GRAFTING IN HEMOPHILIA WITH A PREPARATION OF THROMBIN AND SULFANILAMIDE
- 30 June 1945
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 128 (9) , 656-657
- https://doi.org/10.1001/jama.1945.92860260001010
Abstract
Operative procedures on patients with hemophilia are not often undertaken because of the high postoperative mortality. Excessive bleeding following such a simple operation as tooth extraction has been a common cause of death.1 Recently the use of certain active thrombin preparations has made tooth extraction in hemophilia a relatively safe procedure.2 To our knowledge skin grafting has not been attempted in hemophilia, largely because of the likelihood of uncontrolled bleeding from the donor site. The present report concerns a successful skin graft operation on a patient with hemophilia by means of a preparation of thrombin3 and sulfanilamide4 to control the bleeding from the donor site. REPORT OF CASE W. M., a white man aged 26, hemophilic, of Irish descent, was admitted for the fourteenth time on March 6, 1944. His previous admissions had been for bleeding from a cut lip, from the buccal mucosa, for epistaxes, forThis publication has 1 reference indexed in Scilit:
- THE COAGULATION DEFECT IN HEMOPHILIA. THE EFFECT IN HEMOPHILIA OF INTRAMUSCULAR ADMINISTRATION. OF A GLOBULIN SUBSTANCE DERIVED FROM NORMAL HUMAN PLASMA 1Journal of Clinical Investigation, 1937