Gastrectomy and Iron Absorption: Effects of Bleeding, Iron Loading and Ascorbic Acid in Rats.

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Abstract
Gastrectomlzed rats developed iron deficiency because of decreased absorption of iron. Although these animals absorbed almost normal quantities of iron from test doses when they were iron replete, they were unable to increase absorption of iron appropriately in response to iron depletion. This suggested that iron deficiency occurred after gastrectomy because of an inability to adjust absorption in response to changes in the body requirement.