Metabolic effects of electrical stimulation of mammalian tissues in vitro

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Abstract
Tissue slices of guinea pig brain cortex, kidney cortex and lung, and portions of rat diaphragm were exposed to fluctuating electric currents in vitro. These caused a mean increase of 51% in the rate of brain cortex respiration and an accompanying increase of 56% in aerobic glycolysis. The mean increase in the respiration of diaphragm was 39% with an increase of 47% in aerobic glycolysis. The impulses increased respiration of lung slices by 19% but gave no increase in aerobic glycolysis. No response to the impulses was obtained with kidney slices.