Treatment of perennial allergic rhinitis by local hyperthermia.

Abstract
Patients (95) with documented perennial allergic rhinitis were treated with local hyperthermia of the nasal passages in a randomized double-blind trial. The treatment consisted of 1 series of three 30-min insufflations of humidified air at 43.degree. C at a 2-h interval. In the active treatment group, 75% (P < 0.00003) and 68% (P < 0.00001) of the patients were free of symptoms 1 wk and 1 mo., respectively, after treatment, compared with a 28% and 17% response in the placebo group. Local hyperthermia is effective in the treatment of perennial allergic rhinitis.