Blood levels of proteinase inhibitors in pregnancy

Publisher Website
Google Scholar
Abstract
Plasma volume, serum .varies.2-macroglobulin, .varies.1-antitrypsin, C.hivin.1 inactivator, .varies.2-antiplasmin and plasma antithrombin III were measured in 10 pregnant women at gestation periods of 12-14 and 37-38 wk. In order to investigate the regulation of coagulation and fibrinolytic systems in pregnancy, the proteinase inhibitors were also measured in 10 non-pregnant healthy women. There was a significant increase in the .varies.1-antitrypsin concentration and significant decreases in .varies.2-macroglobulin and C.hivin.1 inactivator, but the total circulating quantity of all the proteinase inhibitors was significantly increased.