Suzuki Cross-Couplings of Unactivated Secondary Alkyl Bromides and Iodides
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- 14 January 2004
- journal article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 126 (5) , 1340-1341
- https://doi.org/10.1021/ja039889k
Abstract
The capacity to employ unactivated alkyl electrophiles as coupling partners will markedly increase the already exceptional utility of metal-catalyzed cross-coupling processes. This communication describes the development of a method that achieves the first Suzuki reactions of unactivated secondary alkyl bromides and iodides. The ability to couple readily available, easy-to-handle boronic acids is an attractive feature of this catalyst system.Keywords
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