Observations on Metabolism of Aldosterone in Man

Publisher Website
Google Scholar
Abstract
In the evaluation of adrenal cortical function by laboratory tests, the essential diagnostic data are the concentrations of hormones in plasma or their metabolites in urine. After a baseline has been established, stimulation with corticotrophin (ACTH) and suppression with dexamethasone give valuable information on adrenal responsiveness to and dependence on ACTH and on the inhibition of pituitary ACTH secretion. The present report deals with the interpretation of the basal measurements in patients with different rates of secretion or metabolism. Since some excellent reports on the secretion and metabolism of cortisol have been published (1), special attention will be directed to