Zinc Balance before and during Treatment with Bendroflumethiazide
- 12 January 1980
- journal article
- research article
- Published by Wiley in Acta Medica Scandinavica
- Vol. 208 (1-6) , 265-267
- https://doi.org/10.1111/j.0954-6820.1980.tb01191.x
Abstract
The present study gives full balance data for Zn in 2 healthy individuals before and during treatment with chlorthalidone. Positive Zn balances were noted in both subjects without therapy. During chlorthalidone treatment the balances changed in a negative direction. The normal or slightly increased serum Zn values, which were seen during diuretic treatment despite increased urinary Zn losses, cannot be explained by increased Zn absorption. Depletion of Zn in tissues seems likely.Keywords
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