Sealing of Developmental Pits and Fissures: IV. Measurement of In Vivo Fluoride Pickup by Electron Microprobe X-Ray Spectrophotometry

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Abstract
Analysis with an electron microprobe X-ray spectrophotometer revealed that high levels of fluoride were retained in enamel 30 or more days after in vivo application of a fluoride-releasing polyurethane adhesive coating to human teeth. Analyses of calcium and phosphorus concentrations also indicate that remineralization occurred after application of the polyurethane, despite preliminary acid etching.